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Potentiation, activation and blockade of GABAA receptors of clonal murine hypothalamic GT1-7 neurones by propofol.

1. The actions of GABA and the intravenous general anaesthetic propofol (2,6-diisopropylphenol) on GABAA receptors of self-replicating GT1-7 hypothalamic neurones were investigated by the patch clamp technique. 2. GABA (1 microM-1 mM) dose-dependently activated inward currents with an EC50 of 27 mic...

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Bibliografische gegevens
Hoofdauteurs: Adodra, S., Hales, T. G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909023/
https://ncbi.nlm.nih.gov/pubmed/7582526
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