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High frequency of CD8+ cytotoxic T-lymphocyte precursors specific for herpes simplex viruses in persons with genital herpes.

Herpes simplex virus (HSV)-specific CD8+ cytotoxic T lymphocytes (CTL) have rarely been detected in humans, presumably because of virus-induced mechanisms that downregulate major histocompatibility complex class I expression. We have developed a method that has allowed us to consistently demonstrate...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Posavad, C M, Koelle, D M, Corey, L
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190896/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.8165-8168.1996
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