Locomotor activation and dopamine release produced by nicotine and isoarecolone in rats.

1. Isoarecolone was approximately 250 times less potent than nicotine as an inhibitor of [3H]-nicotine binding to rat brain membranes. Isoarecolone failed to inhibit the binding of the nicotinic ligand [125I]-alpha-bungarotoxin or of the muscarinic ligand [3H]-QNB. 2. Nicotine (0.01-30 microM) evoke...

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Bibliografski detalji
Glavni autori: Whiteaker, P., Garcha, H. S., Wonnacott, S., Stolerman, I. P.
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908939/
https://ncbi.nlm.nih.gov/pubmed/8640351
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