Foot-and-mouth disease virus 2A protease mediates cleavage in attenuated Sabin 3 poliovirus vectors engineered for delivery of foreign antigens.

Poliovirus vectors are being studied as potential vaccine delivery systems, with foreign genetic sequences incorporated as part of the viral genome. The foreign sequences are expressed as part of the viral polyprotein. Addition of proteolytic cleavage sites at the junction of the foreign polypeptide...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Mattion, N M, Harnish, E C, Crowley, J C, Reilly, P A
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892938/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.8124-8127.1996
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!