Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector.

Muscle-directed gene transfer is being considered for the treatment of several metabolic diseases, including hemophilia and Duchene's muscular dystrophy. Previous efforts to target this tissue for somatic delivery with various vector systems have resulted in transient expression due to silencing of...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Xiao, X, Li, J, Samulski, R J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190884/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892935/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.8098-8108.1996
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