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Mutations in the carboxyl-terminal hydrophobic sequence of human cytomegalovirus glycoprotein B alter transport and protein chaperone binding.

Human cytomegalovirus glycoprotein B (gB) plays a role in the fusion of the virion envelope with the host cell membrane and in syncytium formation in infected cells. Hydrophobic sequences at the carboxyl terminus, amino acids (aa) 714 to 771, anchor gB in the lipid bilayer, but the unusual length of...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Zheng, Z, Maidji, E, Tugizov, S, Pereira, L
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190876/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.8029-8040.1996
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