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Differences in intrinsic efficacy of benzodiazepines are reflected in their concentration-EEG effect relationship.

1. The relevance of EEG effect parameters as a measure of the central nervous system effects of benzodiazepines was evaluated. The concentration-EEG effect relationships of the benzodiazepine agonist midazolam, partial agonist bretazenil, antagonist flumazenil and inverse agonist Ro 19-4603 were qua...

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Bibliografiske detaljer
Main Authors: Mandema, J. W., Kuck, M. T., Danhof, M.
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908634/
https://ncbi.nlm.nih.gov/pubmed/1350744
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