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Interaction of the central analgesic, tramadol, with the uptake and release of 5-hydroxytryptamine in the rat brain in vitro.

1. Tramadol is a centrally acting analgesic with low opioid receptor affinity and therefore presumably other mechanisms of analgesic action. Tramadol inhibits noradrenaline uptake but since 5-hydroxytryptamine (5-HT) is also involved in the modulation of pain perception, we tested the effects of tra...

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Hlavní autoři: Driessen, B., Reimann, W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908625/
https://ncbi.nlm.nih.gov/pubmed/1596676
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