Prevention by blockade of angiotensin subtype1-receptors of the development of genetic hypertension but not its heritability.

1. We determined whether early inhibition of angiotensin II subtype1 (AT1) receptors by the newly synthesized nonpeptidic antagonist, A-81988, can attenuate the development of hypertension in spontaneously hypertensive rats (SHR) and if the altered blood pressure phenotype can be passed on to the su...

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Main Authors: Madeddu, P., Anania, V., Varoni, M. V., Parpaglia, P. P., Demontis, M. P., Fattaccio, M. C., Palomba, D., Pollock, D., Glorioso, N.
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908501/
https://ncbi.nlm.nih.gov/pubmed/7582472
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