Intracellular expression of human immunodeficiency virus type 1 (HIV-1) protease variants inhibits replication of wild-type and protease inhibitor-resistant HIV-1 strains in human T-cell lines.
The enzymatic activity of the human immunodeficiency type 1 (HIV-1) protease (PR) is crucial to render HIV-1 virions mature and infectious. Hence, genetic intervention strategies based on trans-dominant (td) variants of the HIV-1 PR might be an alternative to current pharmacological and gene therapy...
Guardado en:
| Publicado en: | J Virol |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1996
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8892897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.11.7765-7772.1996 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|