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CI988, a selective antagonist of cholecystokininB receptors, prevents morphine tolerance in the rat.

1. The effect of chronic treatment with CI988, a recently developed selective antagonist of cholecystokinin type-B receptors (CCKB receptors) on the tolerance to morphine analgesia was studied in rats with the hot plate test. 2. Morphine tolerance was induced with the use of two paradigms. Morphine...

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Bibliographic Details
Main Authors: Xu, X. J., Wiesenfeld-Hallin, Z., Hughes, J., Horwell, D. C., Hökfelt, T.
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908430/
https://ncbi.nlm.nih.gov/pubmed/1628146
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