Effects of propafenone on 45Ca movements and contractile responses in vascular smooth muscle.

1. In rat isolated aorta the class Ic antiarrhythmic drug, propafenone, dose-dependently inhibited the contractile responses induced by high K (80 mM) and noradrenaline (NA, 10(-5) M), the IC50s being 2.5 +/- 0.7 x 10(-6) M and 8.7 +/- 0.8 x 10(-6) M, respectively. These inhibitory actions were also...

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Hlavní autoři: Carrón, R., Pérez-Vizcaino, F., Delpón, E., Tamargo, J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908362/
https://ncbi.nlm.nih.gov/pubmed/1884101
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