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A quantitative investigation into the dependence of Ca2+ mobilisation on changes in inositol 1,4,5-trisphosphate levels in the stimulated neutrophil.

1. The coupling of N-formyl-methionyl-leucyl-phenylalanine (fMet-Leu-Phe) receptor stimulation to Ca2+ mobilisation has been investigated in the human neutrophil by measuring the concentration-effect curves for inositol 1,4,5-trisphosphate (IP3) formation and Ca2+ mobilisation. 2. fMet-Leu-Phe-depen...

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Bibliographic Details
Main Authors: Thompson, N. T., Bonser, R. W., Tateson, J. E., Spacey, G. D., Randall, R. W., Hodson, H. F., Garland, L. G.
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908335/
https://ncbi.nlm.nih.gov/pubmed/1884113
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