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Cross tachyphylaxis to endothelin isopeptide-induced hypotension: a phenomenon not seen with proendothelin.

1. In anaesthetized rats, an i.v. injection of endothelin-1 (0.25 nmol kg-1) evoked a rapidly appearing (maximal effect within 15 s) and short lasting (3 min) fall in blood pressure with tachyphylaxis occurring so that it was reduced by 50% by the last of 4 injections given 10 min apart. This proper...

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Sonraí Bibleagrafaíochta
Main Authors: Le Monnier de Gouville, A. C., Cavero, I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1991
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908272/
https://ncbi.nlm.nih.gov/pubmed/1786522
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