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ICI D7114 a novel selective beta-adrenoceptor agonist selectively stimulates brown fat and increases whole-body oxygen consumption.

1. ICI D7114 is a novel, beta-adrenoceptor agonist which stimulates whole body oxygen consumption in conscious rats, cats and dogs and brown adipose tissue (BAT) activity in conscious rats. Treatment of rats with ICI D7114 stimulated oxygen consumption (ED50, 0.04 mg kg-1, p.o.) and BAT mitochondria...

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Detalhes bibliográficos
Main Authors: Holloway, B. R., Howe, R., Rao, B. S., Stribling, D., Mayers, R. M., Briscoe, M. G., Jackson, J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908265/
https://ncbi.nlm.nih.gov/pubmed/1686210
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