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Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene.

1. The effects of 10 mg (+)- and (-)-chlorpheniramine and 5 mg (+)- and (-)-dimethindene on daytime sleep latencies, digit symbol substitution and subjective assessments of mood and well-being were studied in 6 healthy young adult humans. Each subject also took 5 mg triprolidine hydrochloride as an...

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Autors principals: Nicholson, A. N., Pascoe, P. A., Turner, C., Ganellin, C. R., Greengrass, P. M., Casy, A. F., Mercer, A. D.
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908262/
https://ncbi.nlm.nih.gov/pubmed/1686208
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