Human papillomavirus type 11 and 16 E5 represses p21(WafI/SdiI/CipI) gene expression in fibroblasts and keratinocytes.

Here we report that the E5 proteins of human papillomavirus type 11 (HPV-11) and HPV-16 suppressed the expression of the p21(WafI/SdiI/CipI) tumor suppressor gene in NIH 3T3 cells and immortalized human keratinocytes. The promoter activity of p21 was repressed by E5 of HPV-11 and -16, suggesting tha...

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Main Authors: Tsao, Y P, Li, L Y, Tsai, T C, Chen, S L
格式: Artigo
語言:Inglês
出版: 1996
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC190821/
https://ncbi.nlm.nih.gov/pubmed/8892872
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