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Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis.

1. Experiments have been performed in order to analyse the mechanism whereby SCA40, a new imidazo[1,2-a]pyrazine derivative relaxes airway smooth muscle. 2. SCA40 (0.01-10 microM) caused a complete and concentration-dependent relaxation of guinea-pig isolated trachea contracted with 20 mM KCl but fa...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Laurent, F., Michel, A., Bonnet, P. A., Chapat, J. P., Boucard, M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908044/
https://ncbi.nlm.nih.gov/pubmed/7682131
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