Cytotoxic T-lymphocyte clones specific for an immunodominant epitope display discerning antagonistic response to naturally occurring Epstein-Barr virus variants.

In the present study we have identified Epstein-Barr virus isolates which encode variant sequences within an HLA B35-restricted immunodominant cytotoxic T-lymphocyte (CTL) epitope that act as natural antagonists and can inhibit CTL activity on the wild-type epitope. This effect can be demonstrated i...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Khanna, R, Burrows, S R, Silins, S L, Moss, D J, Poulsen, L M, Burrows, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190794/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8794388/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.10.7306-7311.1996
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