Pterins inhibit nitric oxide synthase activity in rat alveolar macrophages.

1. The synthesis of nitrite and citrulline from L-arginine by immune-stimulated rat alveolar macrophages and the modulation of this synthesis were studied. 2,4-Diamino-6-hydroxypyrimidine (DAHP), 6R-5,6,7,8-tetrahydro-L-biopterin (BH4) and L-sepiapterin were potent inhibitors of the recombinant inte...

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Hauptverfasser: Jorens, P. G., van Overveld, F. J., Bult, H., Vermeire, P. A., Herman, A. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907912/
https://ncbi.nlm.nih.gov/pubmed/1281717
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