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The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia.

1. The hyperalgesic activities in rats of interleukin-1 beta (IL-1 beta), IL-6, IL-8, tumour necrosis factor alpha (TNF alpha) and carrageenin were investigated. 2. IL-6 activated the previously delineated IL-1/prostaglandin hyperalgesic pathway but not the IL-8/sympathetic mediated hyperalgesic pat...

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Autors principals: Cunha, F. Q., Poole, S., Lorenzetti, B. B., Ferreira, S. H.
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907751/
https://ncbi.nlm.nih.gov/pubmed/1472964
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