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Modulation by opioids and by afferent sensory neurones of prostanoid protection of the rat gastric mucosa.

1. Pretreatment with capsaicin, to deplete sensory neuropeptides from primary afferent neurones or the administration of morphine (9 mg kg-1, i.v.), which can inhibit neuropeptide release, augmented gastric mucosal injury induced by a 5 min challenge with intragastric ethanol in the rat, as assessed...

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Bibliographic Details
Main Authors: Esplugues, J. V., Whittle, B. J., Moncada, S.
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907680/
https://ncbi.nlm.nih.gov/pubmed/1393283
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