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Regional differences in endothelin converting enzyme activity in rat brain: inhibition by phosphoramidon and EDTA.

1. It has been demonstrated previously that conversion of big endothelin-1 (bET-1) to endothelin-1 (ET-1) is inhibited in vitro and in vivo by phosphoramidon. In addition, ET-1 binding sites and mRNA have been shown within the brain. Here we expand upon our previous observation that rat brain contai...

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Detalhes bibliográficos
Main Authors: Warner, T. D., Budzik, G. P., Matsumoto, T., Mitchell, J. A., Förstermann, U., Murad, F.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907670/
https://ncbi.nlm.nih.gov/pubmed/1393292
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