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MDL 27,531 selectively reverses strychnine-induced seizures in mice

1 Strychnine-sensitive glycine receptors are primarily localized in the brainstem and spinal cord where they are the major mediators of postsynaptic inhibition. A compound which acts functionally like a glycine receptor agonist would be potentially useful as a pharmacological tool and as a therapeut...

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Detalhes bibliográficos
Main Authors: Kehne, John H., Kane, John M., Miller, Francis P., Ketteler, Herbert J., Braun, Donald L., Senyah, Yaw, Chaney, Stephen F., Abdallah, Abdulmuniem, Dudley, Mark W., Ogden, Ann Marie, Palfreyman, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907658/
https://ncbi.nlm.nih.gov/pubmed/1327393
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