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A previously unidentified host protein protects retroviral DNA from autointegration

Integration of a DNA copy of the viral genome into a host chromosome is an essential step in the retrovirus life cycle. The machinery that carries out the integration reaction is a nucleoprotein complex derived from the core of the infecting virion. To successfully integrate into host DNA, the viral...

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Hlavní autoři: Lee, Myung Soo, Craigie, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC19075/
https://ncbi.nlm.nih.gov/pubmed/9465049
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