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Quantitative Intra-Individual Monitoring of BCR-ABL Transcript Levels in Archival Bone Marrow Trephines of Patients with Chronic Myeloid Leukemia

We established a quantitative real-time RT-PCR assay for the detection of chimeric BCR-ABL transcripts in archival formalin-fixed bone marrow trephines, both acrylate-embedded and paraffin-embedded. This new methodology enables determination of transcript levels in direct comparison to histopatholog...

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Autors principals: Bock, Oliver, Lehmann, Ulrich, Kreipe, Hans
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907367/
https://ncbi.nlm.nih.gov/pubmed/12552081
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