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Quantification of bcl-2/JH Fusion Sequences and a Control Gene by Multiplex Real-Time PCR Coupled with Automated Amplicon Sizing by Capillary Electrophoresis

Follicular lymphoma is characterized by the presence of the t(14;18)(q32;q21) chromosomal translocation which juxtaposes the bcl-2 gene at 18q21 with the immunoglobulin heavy chain locus at 14q32. Quantification of t(14;18) carrying cells in FL patients can be achieved by real-time PCR, a highly sen...

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Autors principals: Sanchez-Vega, Beatriz, Vega, Francisco, Medeiros, L. Jeffrey, Lee, Ming S., Luthra, Rajyalakshmi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907359/
https://ncbi.nlm.nih.gov/pubmed/12411590
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