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Rapid and Accurate Detection of Monoclonal Immunoglobulin Heavy Chain Gene Rearrangement by DNA Melting Curve Analysis in the LightCycler System

The detection of immunoglobulin heavy chain gene rearrangement (IgH-R) is a standard tool for distinguishing polyclonal from monoclonal B-cell populations. Current DNA-based polymerase chain reactions (PCR) strategies can diagnose monoclonal IgH-R either by measuring the length of the amplicon or by...

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Main Authors: Xu, Dongsheng, Du, Juan, Schultz, Cynthia, Ali, Ayesha, Ratech, Howard
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907354/
https://ncbi.nlm.nih.gov/pubmed/12411589
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