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Novel Fluorescent Ligase Detection Reaction and Flow Cytometric Analysis of SYT-SSX Fusions in Synovial Sarcoma

Synovial sarcomas (SS) are characterized by the t(X;18)(p11;q11) translocation and its resultant fusion gene, SYT-SSX. Two homologues of the SSX gene (ie, SSX1 and SSX2) are involved in the vast majority of SS and the SYT-SSX1 type of fusion has been associated with inferior clinical outcome. Thus,...

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Autors principals: Gaffney, Robyn, Chakerian, Artemis, O’Connell, John X., Mathers, Joan, Garner, Kelly, Joste, Nancy, Viswanatha, David S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907321/
https://ncbi.nlm.nih.gov/pubmed/12707378
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