Recombinant adeno-associated virus-mediated high-efficiency, transient expression of the murine cationic amino acid transporter (ecotropic retroviral receptor) permits stable transduction of human HeLa cells by ecotropic retroviral vectors.

Adeno-associated virus has a broad host range, is nonpathogenic, and integrates into a preferred location on chromosome 19, features that have fostered development of recombinant adeno-associated viruses (rAAV) as gene transfer vectors for therapeutic applications. We have used an rAAV to transfer a...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Bertran, J, Miller, J L, Yang, Y, Fenimore-Justman, A, Rueda, F, Vanin, E F, Nienhuis, A W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190719/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8794313/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.10.6759-6766.1996
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