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Persistent reovirus infections of L cells select mutations in viral attachment protein sigma1 that alter oligomer stability.

During maintenance of L-cell cultures persistently infected with reovirus, mutations are selected in viruses and cells. Cells cured of persistent infection support growth of viruses isolated from persistently infected cultures (PI viruses) significantly better than that of wild-type (wt) viruses. In...

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Bibliographic Details
Published in:J Virol
Main Authors: Wilson, G J, Wetzel, J D, Puryear, W, Bassel-Duby, R, Dermody, T S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190700/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8794294/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.10.6598-6606.1996
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