Repressor element-1 silencing transcription factor/neuronal restrictive silencer factor (REST/NRSF) can regulate HSV-1 immediate-early transcription via histone modification

BACKGROUND: During primary infection of its human host, Herpes Simplex Virus Type-1 (HSV-1) establishes latency in neurons where the viral genome is maintained in a circular form associated with nucleosomes in a chromatin configration. During latency, most viral genes are silenced, although the mole...

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Bibliografiske detaljer
Main Authors: Pinnoji, Rajeswara C, Bedadala, Gautam R, George, Beena, Holland, Thomas C, Hill, James M, Hsia, Shao-chung V
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906746/
https://ncbi.nlm.nih.gov/pubmed/17555596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-56
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