LPS-stimulated human gingival fibroblasts inhibit the differentiation of monocytes into osteoclasts through the production of osteoprotegerin

Periodontitis is an inflammatory bone disease caused by Gram-negative anaerobic bacteria, but the precise mechanism of bone destruction remains unknown. Activated T lymphocytes secrete receptor activator of NF-κB ligand (RANKL) and support the differentiation of monocytes into mature osteoclasts. Th...

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Autori principali: Nagasawa, T, Kobayashi, H, Kiji, M, Aramaki, M, Mahanonda, R, Kojima, T, Murakami, Y, Saito, M, Morotome, Y, Ishikawa, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906523/
https://ncbi.nlm.nih.gov/pubmed/12390325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01990.x
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