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IL-10 enhances B-cell IgE synthesis by promoting differentiation into plasma cells, a process that is inhibited by CD27/CD70 interaction

Interleukin-10 (IL-10) is a major regulatory cytokine of inflammatory responses that is considered to play an important role in specific immunotherapy. However, whether IL-10 enhances or inhibits B-cell IgE production has remained a matter of contention. To clarify the effect of IL-10 on IgE synthes...

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Autori principali: Kobayashi, N, Nagumo, H, Agematsu, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906463/
https://ncbi.nlm.nih.gov/pubmed/12197885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01932.x
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