Preservation of clonal heterogeneity of the Pneumocystis carinii-specific CD4 T cell repertoire in HIV infected, asymptomatic individuals

The loss of CD4 lymphocytes in HIV disease associates with opportunistic infections. Since diverse CD4 T cell clones respond to an opportunistic pathogen, we asked whether CD4 depletion deletes selected clones in the repertoire (vertical depletion) or it affects all clones by reducing the cell numbe...

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Bibliographic Details
Main Authors:	LI PIRA, G, FENOGLIO, D, BOTTONE, L, TERRANOVA, P, PONTALI, E, CAROLI, F, SERI, M, CAILLIEZ, J-C, KOOPMAN, G, ACCOLLA, R, DEL GALDO, F, ABBATE, G, DE PALMA, R, MANCA, F
Format:	Artigo
Language:	Inglês
Published:	Blackwell Science Inc 2002
Subjects:	Original Articles
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1906359/ https://ncbi.nlm.nih.gov/pubmed/11982603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01799.x
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Preservation of clonal heterogeneity of the Pneumocystis carinii-specific CD4 T cell repertoire in HIV infected, asymptomatic individuals

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