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The arthritogenic adjuvant squalene does not accumulate in joints, but gives rise to pathogenic cells in both draining and non-draining lymph nodes

A single intradermal injection of the adjuvant-oil squalene induces T cell-mediated arthritis in DA rats. The chain of events leading from non-specific provocation of the immune system to arthritis, with clinical similarities to rheumatoid arthritis, is largely undetermined. Here, we combined in viv...

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Hlavní autoři: HOLM, B C, SVELANDER, L, BUCHT, A, LORENTZEN, J C
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906311/
https://ncbi.nlm.nih.gov/pubmed/11966758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01783.x
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