Generation in vitro of B-cell chronic lymphocytic leukaemia-proliferative and specific HLA class-II-restricted cytotoxic T-cell responses using autologous dendritic cells pulsed with tumour cell lysate

Immunotherapy using dendritic cells has shown encouraging results in both haematological and non-haematological malignancies. In this study, monocyte-derived dendritic cells from patients with B-CLL were cultured for 6 days in the presence of IL-4 and GM-CSF. Autologous B-CLL T-cells were cultured a...

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Hlavní autoři: Goddard, R V, Prentice, A G, Copplestone, J A, Kaminski, E R
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2001
Témata:
Cancer Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906182/
https://ncbi.nlm.nih.gov/pubmed/11678895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01617.x
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