Effect of 51p1-related gene copy number (V1–69 locus) on production of hepatitis C-associated cryoglobulins

Monoclonal IgM in type II mixed cryoglobulins (MC) preferentially use 51p1-related immunoglobulin V(H) genes. In normal preimmune B lymphocytes, 51p1-related gene expression is proportional to the germ-line gene dosage, which can be 0–4. To determine whether 51p1-related gene dosage influences the o...

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Detalhes bibliográficos
Main Authors: Sasso, E H, Ghillani, P, Musset, L, Piette, J C, Cacoub, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Immunity to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905958/
https://ncbi.nlm.nih.gov/pubmed/11168003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01406.x
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