Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication.

The human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) contains two binding sites for the NF-kappa B/Rel family of transcription factors which are required for the transcriptional activation of viral genes by inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha)...

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Pubblicato in:	J Virol
Autori principali:	Beauparlant, P, Kwon, H, Clarke, M, Lin, R, Sonenberg, N, Wainberg, M, Hiscott, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190591/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8709193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.9.5777-5785.1996
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