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K-ras Mutation and p16 and Preproenkephalin Promoter Hypermethylation in Plasma DNA of Pancreatic Cancer Patients: In Relation to Cigarette Smoking

OBJECTIVES: To examine the profiles of K-ras mutations and p16 and preproenkephalin (ppENK) promoter hypermethylation and their associations with cigarette smoking in pancreatic cancer patients. METHODS: In plasma DNA of 83 patients with untreated primary pancreatic ductal adenocarcinoma, DNA hyperm...

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Detalhes bibliográficos
Main Authors: Li, Jiao, Zhu, Jijiang, Hassan, Manal M., Evans, Douglas B., Abbruzzese, James L., Li, Donghui
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905887/
https://ncbi.nlm.nih.gov/pubmed/17198183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.mpa.0000246665.68869.d4
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