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Point mutations in the promoter region of the CYBB gene leading to mild chronic granulomatous disease

Chronic granulomatous disease (CGD) is a clinical syndrome of recurrent bacterial and fungal infections caused by a rare disorder of phagocytic cells. In CGD, the phagocytes are unable to generate oxygen radicals after stimulation of these cells, due to a defect in the NADPH oxidase system. This NAD...

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Hlavní autoři: Weening, R S, De Boer, M, Kuijpers, T W, Neefjes, V M E, Hack, W W M, Roos, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905790/
https://ncbi.nlm.nih.gov/pubmed/11122248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01405.x
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