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Lack of pharmacokinetic interaction between intravenous 2',3'-dideoxyinosine and 3'-azido-3'-deoxythymidine in rats.

We investigated the pharmacokinetic interaction between 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxyinosine (ddI), given to rats by intravenous injection. For both compounds, the clearances, terminal half-lives, and fractions of the dose excreted unchanged in urine were not altered by the othe...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Wientjes, M G, Au, J L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190576/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1622182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.3.665
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