CD8(+) T cells are crucial for the ability of congenic normal mice to reject highly immunogenic sarcomas induced in nude mice with 3-methylcholanthrene

An attempt was made to identify the selection pressures put upon a growing tumour by CD8(+) T cells. To this end tumours induced with 3-methylcholanthrene in T cell-deficient nude mice and in congenic T cell-competent nu/+ mice were transplanted to nu/+ recipients. The rejection rate of the sarcomas...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Boesen, M, Svane, I M, Engel, A-M, Rygaard, J, Thomsen, A R, Werdelin, O
التنسيق: Artigo
اللغة:Inglês
منشور في: Blackwell Science Inc 2000
الموضوعات:
Cancer Immunology/Therapy
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905705/
https://ncbi.nlm.nih.gov/pubmed/10931133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01292.x
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