Target antigens for anti-neutrophil cytoplasmic autoantibodies (ANCA) are on the surface of primed and apoptotic but not unstimulated neutrophils

The reaction of ANCA with ANCA antigens on the surface of neutrophils may play a critical role in the pathogenesis of ANCA vasculitis. Therefore, an understanding of the circumstances that result in surface expression of these antigens is important for an understanding of pathogenic mechanisms. In t...

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Main Authors: Yang, J J, Tuttle, R H, Hogan, S L, Taylor, J G, Phillips, B D, Falk, R J, Jennette, J C
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
Assuntos:
Vasculitis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905660/
https://ncbi.nlm.nih.gov/pubmed/10886255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01228.x
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