Suppression of ongoing experimental allergic encephalomyelitis (EAE) in Lewis rats: synergistic effects of myelin basic protein (MBP) peptide 68–86 and IL-4

Mucosal myelin autoantigen administration effectively prevented EAE, but mostly failed to treat ongoing EAE. Patients with multiple sclerosis (MS), for which EAE is considered an animal model, did not benefit from oral treatment with bovine myelin. We anticipated that autoantigen, administered toget...

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Autori principali: Xu, L-Y, Huang, Y-M, Yang, J-S, Van Der Meide, P H, Link, H, Xiao, B-G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
Soggetti:
Neuroimmunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905554/
https://ncbi.nlm.nih.gov/pubmed/10844533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01233.x
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