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Molecular determinants of polyreactive antibody binding: HCDR3 and cyclic peptides
Human monoclonal antibody 63 (mAb63) is an IgM/λ polyreactive antibody that binds to multiple self and non-self antigens. The molecular basis of polyreactivity is still unclear. The present study was initiated to prepare a recombinant Fab of mAb63 and use it to study the determinants involved in pol...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905533/ https://ncbi.nlm.nih.gov/pubmed/10606966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01096.x |
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