Inhibition of apoptosis by ionomycin and zinc in peripheral blood mononuclear cells (PBMC) of leprosy patients

PBMC from tuberculoid (BT/TT) and lepromatous leprosy (BL/LL) leprosy patients showed spontaneous apoptosis when cultured in the absence of mitogen for 24 h, which was inhibited by anti-tumour necrosis factor-alpha (TNF-α) antibodies. Apoptosis was also inhibited by ionomycin and zinc, which also in...

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Bibliographic Details
Main Authors: GUPTA, A, SHARMA, VK, VOHRA, H, GANGULY, NK
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1999
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905487/
https://ncbi.nlm.nih.gov/pubmed/10403916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00908.x
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