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Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1α (MIP-1α) and MIP-1β) in patients with systemic sclerosis: MCP-1 and MIP-1α may be involved in the development of pulmonary fibrosis

To determine the role of chemokines in the pathogenesis of systemic sclerosis (SSc), we examined serum levels, spontaneous production by peripheral blood mononuclear cells (PBMC), and histological distribution in the affected skin, of MCP-1, MIP-1α and MIP-1β in SSc patients. Serum levels of these c...

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Autors principals: HASEGAWA, M, SATO, S, TAKEHARA, K
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905464/
https://ncbi.nlm.nih.gov/pubmed/10403930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00929.x
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