Cytolytic mechanisms involved in non-MHC-restricted cytotoxicity in Chediak-Higashi syndrome

To determine the mechanisms responsible for the impaired lymphocyte-mediated cytotoxicity in Chediak-Higashi syndrome (CHS), we investigated the killing ability of peripheral blood lymphocytes (PBL) from three patients with CHS using several kinds of target cells that were sensitive to perforin, Fas...

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Detalhes bibliográficos
Main Authors: Nakazawa, T, Agematsu, K, Yasui, K, Onodera, T, Inoue, R, Kaneko, H, Kondo, N, Yamamoto, M, Kayagaki, N, Yagita, H, Okumura, K, Komiyama, A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905392/
https://ncbi.nlm.nih.gov/pubmed/10540167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.01025.x
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