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Mechanism of complement-dependent haemolysis via the lectin pathway: role of the complement regulatory proteins
Mannan-binding lectin (MBL) is an acute phase protein which activates the classical complement pathway at the level of C4 and C2 via two novel serine proteases homologous to C1r and C1s. We recently reported that haemolysis via this lectin pathway requires alternative pathway amplification. The pres...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905373/ https://ncbi.nlm.nih.gov/pubmed/10469045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00998.x |
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